产品货号：
Z33057
中文名称：
ADA抗体
英文名称：
Anti-ADA Antibody (Clone#6D4)
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-ADA Antibody (Clone#6D4) |
| 指标别名 | ADA;Adenosine aminohydrolase;adenosine deaminase |
| 克隆性 | Monoclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC,FCM |
| 基因名称 | ADA |
| 克隆号 | 6D4 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG2b |
| 免疫原 | E.coli-derived human ADA recombinant protein (Position:Q135-L363).Human ADA shares 82.5% and 82.9% amino acid (aa) sequence identity with mouse and rat ADA,respectively. |
| 实际分子量 | 45KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | protein G purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Adenosine Deaminase (also known as adenosine aminohydrolase,or ADA) is an enzyme involved in purine metabolism.Primarily,ADA in humans is involved in the development and maintenance of the immune system.However,ADA association has also been observed with epithelial cell differentiation,neurotransmission,and gestation maintenance.It has also been proposed that ADA,in addition to adenosine breakdown,stimulates release of excitatory amino acids and is necessary to the coupling of A1 adenosine receptors and heterotrimeric G proteins.Adenosine deaminase deficiency leads to pulmonary fibrosis,suggesting that chronic exposure to high levels of adenosine can exacerbate inflammation responses rather than suppressing them.It has also been recognized that adenosine deaminase protein and activity is upregulated in mouse hearts that overexpress HIF-1 alpha,which in part explains the attenuated levels of adenosine in HIF-1 alpha expressing hearts during ischemic stress. |
| Uniprot ID | P00813 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (ZN1928) for Western blot,and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (ZN1866) for IHC(P) and ICC. |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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